The reported STUMP recurrence rate ranges between 8.7% and 11%, but poor data is available in the Literature. It is plausible that SMTs defined as STUMPs may be variants of leiomyomas with unusual pathologic features. On the other hand, some tumors regarded as STUMPs may in reality be underdiagnosed leiomyosarcomas.
What is a STUMP tumor?
Smooth muscle tumor of uncertain malignant potential (STUMP) encompasses a broad group of uterine neoplasms that do not meet the current histologic criteria for a diagnosis of either benign or a malignant tumor.
Is a malignant tumor of smooth muscle?
Leiomyosarcoma is a malignant (cancerous) tumor that arises from smooth muscle Cells There are essentially two types of muscles in the body – voluntary and involuntary.
What is smooth muscle tumor of uncertain malignant potential?
Smooth muscle tumor of uncertain malignant potential, abbreviated STUMP, is an uncommon tumor of the uterine smooth muscle that may behave like a benign tumor or a cancerous tumor.What is a stump medical term?
Medical Definition of stump 1 : the basal portion of a bodily part (as a limb) remaining after the rest is removed. 2 : a rudimentary or vestigial bodily part.
What does uncertain malignant potential mean?
The term smooth uterine muscle of uncertain malignant potential (STUMPs) indicates a group of uterine smooth muscle tumors (SMTs) that cannot be diagnosed unequivocally as benign or malignant.
What is cervical stump?
Cervical stump cancer occurs in the remaining uterine cervix of a woman who has undergone supravaginal hysterectomy for benign diseases such as uterine fibroids, benign ovarian tumors, and postpartum hemorrhage. Cervical stump cancer accounts for 1.6-4.4% of all cervical cancer cases [1-6].
What is a leiomyosarcoma?
Leiomyosarcoma, or LMS, is a type of rare cancer that grows in the smooth muscles. The smooth muscles are in the hollow organs of the body, including the intestines, stomach, bladder, and blood vessels. In females, there is also smooth muscle in the uterus.What is a Symplastic leiomyoma?
symplastic leiomyoma, are rare smooth muscle tumors. that contain cells with moderate to severe cytological. atypia but cell necrosis is absent and mitotic index is. fewer than 10 mf/10 hpf.1 These are benign lesions even. if there is high cellularity, numerous widely distributed.
How can you tell the difference between leiomyosarcoma and leiomyoma?Leiomyosarcoma is not the same as leiomyoma. Leiomyoma also starts in smooth muscles, but it isn’t cancer and it doesn’t spread. SOURCES: Dana-Farber Cancer Institute: “Leiomyosarcoma.”
Article first time published onWhat is atypical leiomyoma?
Atypical leiomyoma is a well-described smooth muscle neoplasm of the uterus. Only 1 study has addressed long-term clinical follow-up in a large series, and little is known about the adequacy of treatment by myomectomy.
What is mitotically active leiomyoma?
Mitotically active leiomyomas occur predominantly in postmenopausal women. They show 5 or more mitoses/10 HPF (Usually 5-15 mitoses/10 HPF), but lack coagulative necrosis and cytologic atypia. In this high power field, 2 typical mitotic figures (MF) are noted.
How fast does sarcoma grow?
Synovial sarcoma is a representative type of slowly growing highly malignant tumor, and it has been reported that in synovial sarcoma cases, a substantial proportion of patients have an average symptomatic period of 2 to 4 years, though in some rare cases, this period has been reported to be longer than 20 years [4].
What is a benign smooth muscle tumor?
Benign smooth muscle tumors include smooth muscle hamartoma and angioleiomyoma. A specific category of leiomyomas are estrogen-receptor positive ones in women. These are similar to uterine leiomyomas and can occur anywhere in the abdomen and abdominal wall.
What is the term for tumor of smooth muscle?
Listen to pronunciation. (LY-oh-MY-oh-sar-KOH-muh) A malignant (cancer) tumor of smooth muscle cells that can arise almost anywhere in the body, but is most common in the uterus, abdomen, or pelvis.
Can stumps grow back?
Regeneration. Stumps (both those on the ground and stumps of removed branches) are sometimes able to regenerate into new trees. Often, a deciduous tree that has been cut will re-sprout in multiple places around the edge of the stump or from the roots.
What are signs of infection of a stump?
- warm, red and tender skin.
- discharge of fluid or pus.
- increasing swelling.
What is ideal stump?
Ideal Stump Skin flaps: skin should be mobile, sensation intact, no scars. Muscles are divided 3 to 5 cm distal to the level of bone resection. Nerves are gently pulled and cut cleanly, so that they retract well proximal to the bone level to reduce the complication of neuroma.
What body parts are removed with a hysterectomy?
Types of hysterectomy surgery A total hysterectomy (top right) removes the uterus and cervix. At the time of a total hysterectomy, your surgeon may also remove the ovaries and fallopian tubes (bottom). An abdominal hysterectomy is a surgical procedure that removes your uterus through an incision in your lower abdomen.
Can you get pregnant after a Supracervical hysterectomy?
Pregnancy after hysterectomy can follow any type of hysterectomy (total or supracervical) and any approach (abdominal, laparoscopic, or vaginal), but the highest risk is with supracervical hysterectomies [3, 5]. Pregnancies after hysterectomy can take one of two forms: early and late presenting.
What is subtotal hysterectomy?
Listen to pronunciation. (sub-TOH-tul HIS-teh-REK-toh-mee) Surgery to remove the uterus, but not the cervix. Also called partial hysterectomy and supracervical hysterectomy.
What is Symplastic transport?
The symplastic pathway: It provides the movement of water from one cell to another cell by plasmodesmata. Symplast, is an inner side of the plasma membrane.
Does anyone survive leiomyosarcoma?
Life expectancy for leiomyosarcoma is often expressed in 5-year survival rates, that is, how many people will be alive 5 years after diagnosis. Leiomyosarcoma 5-year survival rates: Localized (no sign the cancer has spread outside the original site): 63%
Does Chemo work for leiomyosarcoma?
Adriamycin (Doxorubicin) and ifosfamide are the chemotherapy drugs that are currently used to treat leiomyosarcoma. They work well for some people, but not everyone. Doctors think that the drugs gemcitabine and docetaxel (Taxotere) may be better.
How fast does leiomyosarcoma grow?
Leiomyosarcoma is a rare but aggressive type of cancer. It can grow fast and may even double in size in as little as four weeks. The treatment needs to be initiated as soon as possible after its diagnosis. Even after the treatment, there are high chances that this type of cancer will recur.
How rare is uterine sarcoma?
Cancerous cells that develop in its muscles or supporting tissues are called uterine sarcoma. Uterine sarcoma is rare, making up less than 4 percent of all cancers of the uterus. Only 1,200 women are diagnosed with this disease in the United States each year.
Is fibroma malignant?
They can grow in all organs, arising from mesenchyme tissue. The term “fibroblastic” or “fibromatous” is used to describe tumors of the fibrous connective tissue. When the term fibroma is used without modifier, it is usually considered benign, with the term fibrosarcoma reserved for malignant tumors.
Can leiomyoma turn malignant?
In conclusion malignant transformation of benign leiomyoma to leiomyosarcoma, although a rare occurance but can happen in certain patients with large myomas, post menopausal women, rapid growing myomas and in certain subset of leiomyoma.
Are Leiomyomas painful?
Pilar leiomyomas are the most common of the cutaneous types and the lesions are often multiple and painful. A burning or sharp, stabbing pain may occur spontaneously or can be provoked by touch/pressure and cold temperature.
What is red degeneration?
Red degeneration is a hemorrhagic infarction of the uterine leiomyoma, which is a well known complication, especially during pregnancy. Red degeneration occurs in 8% of tumors complicating pregnancy, although the prevalence is about 3% of all uterine leiomyoma.
What does Mitotically mean?
: of, relating to, involving, or occurring by cellular mitosis mitotic cell division mitotic recombination Microtubules move material through the cell and, in particular, form an important component of the mitotic spindle, which is a structure that separates the duplicated sets of chromosomes in the course of cell …
